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researchers in lab
researchers in lab

Our Cancer Clinical Trials

For decades, Mays Cancer Center, home to UT Health San Antonio MD Anderson Cancer Center, has been advancing care through clinical research. These efforts give eligible patients access to the next generation of cancer care while receiving services close to home.

Mays Cancer Center is often among the first places offering eligible patients access to trials of new treatments, including novel cancer drugs. Our clinical trials are making care more precise and giving additional options to people for whom standard treatments aren’t successful. Learn more about our cancer clinical trials.

Our clinical trials expertise also includes cancer therapies specifically for children. Get more information about innovative options available through pediatric cancer clinical trials.

Your peace of mind is important to us. We provide trial participants with ongoing information and support. Find out more about cancer clinical trials.

Clinical trial phases

Clinical trials are studies that answer different types of research questions. Each phase of study explores a different aspect of potential new cancer services.

Clinical trial phases include:

  • Preclinical testing: We conduct new drug studies in cancer cells and tumors growing in mice to show anti-tumor activity and safety before conducting clinical trials in cancer patients. Learn more about our Experimental and Developmental Therapeutics Program and our Cancer Development and Progression Program.
  • Phase I: First-in-human trials enable us to investigate safety, tolerability, effective drug dosing and anti-tumor activity of a new drug in cancer patients. Find out more about our Institute for Drug Development, which hosts our Phase I trials.
  • Phase II: Through these studies in larger groups of cancer patients of the same cancer type, we confirm safety and anti-tumor activity at the highest dose tolerated in Phase I trials.
  • Phase III: When a prospective treatment has shown promise, this type of trial compares the new drug with standard-of-care therapy to evaluate its effectiveness.
  • Phase IV: After the therapy gains Food and Drug Administration (FDA) approval and is on the market, researchers evaluate side effects that occur over time. Phase IV trials are also called post-marketing surveillance.

How to participate in clinical trials

If you’d like to learn more about participating in clinical trials, here’s what to expect:

  • Find out about clinical trial opportunities: Our doctors and research coordinators typically start the conversation about clinical trials if they think you might be eligible. You are also welcome to ask your doctors about clinical trials as an option for your treatment.
  • Learn about specific trials and eligibility: Each trial has eligibility requirements specific to that trial. If you meet the requirements, we explain everything you need to know. We’ll tell you the trial’s purpose, why we are conducting the trial and which services you’ll receive.
  • Complete the consent process: We discuss the risks and benefits of the trial. We also review your rights and responsibilities. For example, you have a right to privacy that includes all trials you participate in. You complete paperwork saying that you agree to participate in the trial. But you are free to change your mind at any time.
  • Follow care instructions: You may need treatments at specific times or extra tests and care appointments as part of the trial. Our research coordinators help you stay on top of next steps.