It’s a medical conundrum. Ionizing radiation, which at first extends the survival of glioblastoma patients after surgery, may later, ironically, help drive the brain cancer’s aggressive, untreatable recurrence. Dr. Sandeep Burma and a team of investigators at the Mays Cancer Center, home to UT Health San Antonio MD Anderson Cancer Center, are studying companion treatments to see if any can eliminate this Jekyll and Hyde property of ionizing radiation.

Glioblastoma-impacted mice lived longer when treated with combination of molecule drug and chemotherapy agent Glioblastoma (GBM), a highly devastating brain tumor, has long posed challenges as effective treatments have remained elusive. Despite responding initially to treatment, GBM patients often experience therapy resistance leading to low long-term survival rates, with only 7.2% of patients surviving beyond […]

An improvement in 6-month progression-free survival warrants additional study in a larger trial, researchers said. The Mays Cancer Center at The University of Texas Health Science Center at San Antonio recently conducted a clinical trial combining two drugs in patients with recurrent, high-grade glioblastoma (GBM). The Mays Cancer Center, one of the four National Cancer […]